Molecular Imaging
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Imaging is a key pillar upon which modern medicine is built. In our lab, we utilize advanced imaging technologies such as positron emission tomography (PET), computed tomography (CT), optical imaging (OI) and multispectral optoacoustic tomography (MSOT) to visualize and glean molecular information about cancer and other diseases.
By developing quantitative imaging methods and precise molecular tracers, we aim to improve early disease detection, assess molecular and functional changes in the disease microenvironment, visualize and quantify pharmacokinetics and pharmacodynamics of novel and established therapies, measure immunological responses, determine the onset of treatment action and asses its efficacy, all in living systems at high spatio-temporal resolution. Representative publications:
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Novel Therapeutics
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We develop nanoparticles and biologics such as antibody fragments and peptides to explore new opportunities in advancing therapies for cancer and other diseases.
Representative Publications:
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Theranostics
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Theranostics is a relatively new field that allows us to bring together our expertise in imaging and therapeutics by developing constructs with dual functionality - imaging and therapy. By doing this, we can evaluate and assess a tumor while treating it simultaneously. This is advantageous as we can leverage a single injection to accomplish multiple goals. It also allows us to gain a better understanding of the treatment localization to the tumor and tailor it for lower off target effects.
Representative Publications
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